She called his 2007 performance at the VMAs one of the most memorable: "He will give an energetic, bombastic, jaw-dropping performance." Adele, who is nominated for seven VMAs, is also scheduled to perform. Only Katy Perry has more VMA nods with nine; Adele is tied with Kanye West with her seven.
Doyle predicted Adele would "bring chills down everybody's spine, if not bring them to tears, too."
Adele has the year's best-selling album with "21," but Doyle notes that her live act hasn't been seen much: Adele was forced to reschedule some concerts earlier this year because of a throat problem.
Lil Wayne's appearance will come a day before the scheduled release of his much-anticipated new album, "Tha Carter IV." Like Brown, he has also performed before on the VMAs.
"Being a nominee and performer on the VMAs once again is an honor because everyone doesn't get that opportunity," he said in statement. "Looking forward to performing on the show, and having 'Tha Carter IV' drop the same week!"